Stroke App:Hub is a mobile application which rapidly connects Stroke Doctor to Emergency Department. Stroke protocol is initiated from emergency department using TiaTele Cart mobile application and enables providers to assess and monitor stroke patients. The solution includes internet audio and video call, secure text and customizable rules with capability to broadcast messages and group calls. Physician scheduler is integrated for the 1st on call and 2nd on call doctors Vascular and Interventional Neurology doctors. Hardware devices includes Telemedicine cart with IP camera, iMac and various wireless medical equipments. The stroke workflow guides the physicians through NIH Stroke Scale assessment and stroke protocol chart as guidelines for diagnosing and making treatment decisions. Patient status with time tracking from ‘Last Known Well’ and ‘Door-to-Needle Time’ is shown for analyzing the stroke protocol execution efficiency.